Hypoglycemia and Anxiety

Written by Jim Folk
Medically reviewed by Marilyn Folk, BScN.
Last updated June 16, 2025

Hypoglycemia and Anxiety: Understanding the Connection and What to Do About It

At first glance, low blood sugar (hypoglycemia) and anxiety might seem like two separate issues—one physical, the other emotional. But for many people, the two are more connected than they realize. If you’ve ever felt shaky, dizzy, irritable, or panicky after skipping a meal or going too long without food, blood sugar may be playing a bigger role in your anxiety than you think.

This article explores the powerful link between hypoglycemia and anxiety, why their symptoms overlap, and how stabilizing blood sugar—alongside good anxiety recovery work—can help you feel more balanced and in control.

What Is Hypoglycemia?

Hypoglycemia is a condition where your blood glucose (sugar) levels fall below normal—typically less than 70 mg/dL (3.9 mmol/L). Because the brain depends on a steady supply of glucose for energy, low blood sugar activates the body’s stress response to try to correct the imbalance.

Common causes of hypoglycemia include:

  • Diabetes medications (especially insulin or sulfonylureas)
  • Skipped meals or long gaps between eating
  • Excessive alcohol consumption
  • Intense exercise without proper nutrition
  • Reactive hypoglycemia (blood sugar crash after eating)
  • Rare conditions like insulinomas or adrenal insufficiency

Even people without diabetes can experience episodes of low blood sugar, especially under stress or when eating habits are inconsistent.

Anxiety Tests

Rate Your Anxiety. Free Online Instant Results!
Take the Test Now!

Shared Symptoms of Hypoglycemia and Anxiety

When blood sugar drops, the body responds by releasing adrenaline, cortisol, and glucagon—stress hormones that try to raise glucose levels quickly. This surge of hormones also creates symptoms nearly identical to anxiety and panic.

Symptoms that Overlap:

This similarity can cause confusion: Am I having a panic attack, or is my blood sugar low? Sometimes, the answer is both.

The Hypoglycemia-Anxiety Feedback Loop

For those already prone to anxiety, hypoglycemia can be a trigger, initiating a cycle that looks like this:

  • You skip a meal or go too long without eating.
  • Blood sugar drops.
  • The body releases stress hormones to fix it.
  • You start feeling shaky, nervous, dizzy—like an anxiety surge.
  • Worry kicks in: “What’s happening to me?” or “Am I going to faint?”
  • Anxiety escalates, making symptoms worse.

And round it goes.

This loop becomes especially frustrating for those with panic disorder, health anxiety, or trauma because the body feels “in danger” even when it isn’t, which can reinforce the brain’s belief that something is wrong.

Anxiety Can Worsen Blood Sugar Regulation

The relationship goes both ways. Chronic anxiety and stress can also impact how the body handles blood sugar. Elevated cortisol levels (a hallmark of chronic stress) increase insulin resistance and make blood sugar swings more likely.

Other ways anxiety can contribute to hypoglycemia include:

  • Skipping meals due to nausea or loss of appetite
  • Increased energy expenditure through nervous tension
  • Overreliance on caffeine
  • Sleep disturbances that affect glucose metabolism

In short, unmanaged anxiety can set the stage for more frequent blood sugar crashes—and more crashes can lead to more anxiety.

Diagnostic Challenges: Anxiety or Hypoglycemia?

Because the symptoms of both conditions are so similar, it’s easy to misattribute one for the other.

To help tell the difference:

  • Use a glucometer: If symptoms strike, a quick check can confirm whether blood sugar is low.
  • Consider timing: Hypoglycemia often occurs after fasting, intense exercise, or a carb-heavy meal (in reactive hypoglycemia). Anxiety may strike in response to specific stressors or thoughts.
  • Observe how symptoms resolve: Hypoglycemic symptoms usually improve within 10–15 minutes of consuming carbohydrates. Anxiety symptoms may take longer and often benefit from relaxation techniques or cognitive strategies.

Still, it’s common for the two to overlap—which is why both blood sugar management and anxiety recovery strategies are important.

The Psychological Impact of Recurrent Hypoglycemia

For people with diabetes or frequent low blood sugar episodes, the fear of hypoglycemia can itself become a source of anxiety—known as hypoglycemia-associated autonomic failure (HAAF). Individuals may become so afraid of symptoms that they:

  • Overeat to avoid lows
  • Avoid exercise or daily activity
  • Experience anticipatory anxiety (worrying they’ll “crash”)

Over time, this can lead to avoidance behaviors, lower confidence in managing health, and even an increase in panic attacks. This highlights how important it is to address both the physical and emotional components of these experiences.

Anxiety Therapy Services

How to Manage Hypoglycemia and Anxiety Together

Managing both conditions involves an integrated approach—supporting your body’s physiology while calming the nervous system and reducing emotional reactivity.

1. Eat Regular, Balanced Meals

Eat every 3–4 hours. Each meal should include complex carbs (like whole grains), protein, and healthy fats. This stabilizes blood sugar and reduces hormonal spikes and crashes.

2. Avoid Skipping Meals

Even unintentionally missing a meal can cause a blood sugar dip that mimics a panic attack.

3. Limit Sugar and Refined Carbs

These can cause sharp spikes followed by sudden drops, especially in sensitive individuals.

4. Reduce or Eliminate Caffeine

Caffeine stimulates the nervous system and can both trigger anxiety and interfere with glucose balance.

5. Practice Daily Deep Relaxation

Engage in deep relaxation, relaxed breathing, progressive muscle relaxation, prayer, or meditation each day to reduce cortisol and improve glucose regulation.

6. Reduce Stress

Chronic stress affects hormone regulation and glucose control. Gentle, consistent stress reduction—through boundaries, lifestyle changes, or support—can make a big difference.

7. Get Consistent, Restorative Sleep

Sleep deprivation increases insulin resistance and anxiety sensitivity. Aim for regular sleep and wake times.

8. Monitor Blood Sugar (If Applicable)

For those with diabetes or reactive hypoglycemia, regular glucose monitoring can catch dips early and build confidence.

9. Cognitive Behavioral Therapy (CBT)

CBT can help reduce catastrophic thinking, manage panic, and address fears related to symptoms or food.

10. Talk to a Professional

Whether it’s an anxiety therapist, dietitian, or medical doctor, support from a professional can make a big difference. An interdisciplinary team approach works best.

Prevention and Peace of Mind

Preventing hypoglycemia isn’t just about avoiding symptoms—it’s also about protecting emotional well-being. The more stable your blood sugar, the more resilient and calm your nervous system becomes.

Simple preventive habits like eating consistently, reducing stress, and taking care of your body go a long way in breaking the cycle of fear and reactivity. The good news? You don’t have to “fix” everything at once. Even small, consistent steps can create real change over time.

Final Thoughts

If you’ve been struggling with anxiety that seems to come out of nowhere, or if you feel panicky when you’re hungry or fatigued, your blood sugar might be part of the picture. The mind and body are deeply connected. One affects the other.

Understanding this link doesn’t mean your anxiety isn’t real. In fact, it’s the opposite. It means your body is trying to help but may be running on an overloaded system (hyperstimulation).

With the right knowledge, care, and support, you can stabilize your health and feel more grounded—mentally, emotionally, and physically.

At anxietycentre.com, we’ve lived this journey and have helped thousands do the same. If you’d like guidance on how to regain control, we’re here to help—step by step, with compassion and expert care.

The combination of good self-help information and working with an experienced anxiety disorder therapist, coach, or counselor is the most effective way to address anxiety and its many symptoms. Until the core causes of anxiety are addressed – which we call the underlying factors of anxiety – a struggle with anxiety unwellness can return again and again. Dealing with the underlying factors of anxiety is the best way to address problematic anxiety.

Additional Resources

Return to our Anxiety Articles page.

anxietycentre.com: Information, support, and therapy for anxiety disorder and its symptoms, including Hypoglycemia and Anxiety: Understanding the Connection and What to Do About It.

References

1. Cryer, P. E. (2007). Hypoglycemia, functional brain failure, and brain death. Journal of Clinical Investigation, 117(4), 868–870.

2. Graveling, A. J., & Frier, B. M. (2010). Impaired awareness of hypoglycaemia: a review. Diabetes & Metabolism, 36(Suppl 3), S64–S74.

3. Hilsted, J., et al. (1984). Sympathetic nervous system in idiopathic orthostatic hypotension and diabetic autonomic neuropathy. Circulation, 69(5), 937–944.

4. Gold, P. W., & Chrousos, G. P. (2002). Organization of the stress system and its dysregulation in melancholic and atypical depression: high vs low CRH/NE states. Molecular Psychiatry, 7(3), 254–275.

5. Gonzalez, J. T., & Stevenson, E. J. (2012). Feeding the brain: The importance of glucose for human cognition. Proceedings of the Nutrition Society, 71(4), 507–518.

6. American Diabetes Association (ADA). Standards of Medical Care in Diabetes – 2024. https://diabetesjournals.org

7. Mayo Clinic. Low blood sugar (hypoglycemia).

8. McEwen, B. S. (2007). Physiology and neurobiology of stress and adaptation: central role of the brain. Physiological Reviews, 87(3), 873–904.

9. van der Valk, E. S., et al. (2015). The effects of stress on glucose metabolism and insulin resistance. Nature Reviews Endocrinology, 11, 455–471.

10. National Institute of Mental Health (NIMH). Anxiety Disorders Overview.

11. Harvard Health Publishing. Foods linked to better brainpower.

12. American Psychological Association (APA). Cognitive Behavioral Therapy for Anxiety Disorders.